We had a fab update back in December from this very handsome chap, Murphy. Jacques treated Murphy back in January 2015 for Granulomatous Meningoencephalitis (GME) and again in the October due to a relapse.

GME is the name given to a kind of inflammation affecting the brain, spinal cord and the meninges (covering of the brain and spinal cord).

It is characterised by focal or dessiminated granulomatous lesions within the brain and/or spinal cord. What causes this disease is not entirely understood although an immune-mediated cause is suspected.

The treatment of GME is a course of subcutaneous injections of Cytosine arabinoside (Cytarabine) which is an antineoplastic agent which acts upon dividing cells by blocking the synthesis of the pyrimidine base of DNA causing premature termination of the chain.

During treatment the patient remains hospitalised given their Chemotoxic status so are barrier nursed. This treatment has demonstrated success in treating GME.

Murphy was a superstar patient and we are very pleased that even with a relapse he is now loving life and doing well. We love the pictures and wish Murphy and his owner lots of fun times and happiness.

dalmatian Murphy on beach
Vet Extra Neurology

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